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Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
J Biol Chem. 2002 Dec 27;277(52):50812-9. doi: 10.1074/jbc.M208108200. Epub 2002 Oct 16.
J Biol Chem. 2002.
PMID: 12386165
Free article.
Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase.
Piechotta K, Garbarini N, England R, Delpire E.
Piechotta K, et al.
J Biol Chem. 2003 Dec 26;278(52):52848-56. doi: 10.1074/jbc.M309436200. Epub 2003 Oct 16.
J Biol Chem. 2003.
PMID: 14563843
Free article.
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The TNF receptor, RELT, binds SPAK and uses it to mediate p38 and JNK activation.
Polek TC, Talpaz M, Spivak-Kroizman T.
Polek TC, et al.
Biochem Biophys Res Commun. 2006 Apr 28;343(1):125-34. doi: 10.1016/j.bbrc.2006.02.125. Epub 2006 Mar 2.
Biochem Biophys Res Commun. 2006.
PMID: 16530727
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Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, Sun D, Elledge SJ, Alessi DR, Kahle KT.
Zhang J, et al.
Sci Rep. 2016 Oct 26;6:35986. doi: 10.1038/srep35986.
Sci Rep. 2016.
PMID: 27782176
Free PMC article.
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