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Targeted replacement of mouse apolipoprotein A-I with human ApoA-I or the mutant ApoA-IMilano. Evidence of APOA-IM impaired hepatic secretion.
J Biol Chem. 2003 Feb 14;278(7):4740-6. doi: 10.1074/jbc.M207335200. Epub 2002 Dec 5.
J Biol Chem. 2003.
PMID: 12471038
Free article.
Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I.
Williamson R, Lee D, Hagaman J, Maeda N.
Williamson R, et al.
Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7134-8. doi: 10.1073/pnas.89.15.7134.
Proc Natl Acad Sci U S A. 1992.
PMID: 1496008
Free PMC article.
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ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes.
Plump AS, Azrolan N, Odaka H, Wu L, Jiang X, Tall A, Eisenberg S, Breslow JL.
Plump AS, et al.
J Lipid Res. 1997 May;38(5):1033-47.
J Lipid Res. 1997.
PMID: 9186920
Free article.
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