A colonization factor (production of lateral flagella) of mesophilic Aeromonas spp. is inactive in Aeromonas salmonicida strains

Appl Environ Microbiol. 2003 Jan;69(1):663-7. doi: 10.1128/AEM.69.1.663-667.2003.

Abstract

The nine laf (lateral flagellum) genes of mesophilic aeromonads are in the Aeromonas salmonicida genome. The laf genes are functional, except for lafA (flagellin gene), which was inactivated by transposase 8 (IS3 family). A pathogenic characteristic of mesophilic aeromonads (lateral flagella) is abolished in this specialized pathogen with a narrow host range.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aeromonas / classification*
  • Aeromonas / pathogenicity*
  • Aeromonas / physiology
  • Animals
  • Bacterial Adhesion
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Biofilms
  • Cell Line
  • Flagella / genetics
  • Flagella / metabolism*
  • Flagellin / genetics*
  • Flagellin / metabolism
  • Gene Deletion
  • Genetic Complementation Test
  • Humans
  • Multigene Family
  • Salmonidae / microbiology*
  • Virulence

Substances

  • Bacterial Proteins
  • Flagellin