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ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics.
Hum Mol Genet. 2003 Jul 15;12(14):1671-87. doi: 10.1093/hmg/ddg184.
Hum Mol Genet. 2003.
PMID: 12837691
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.
Tudor EL, Perkinton MS, Schmidt A, Ackerley S, Brownlees J, Jacobsen NJ, Byers HL, Ward M, Hall A, Leigh PN, Shaw CE, McLoughlin DM, Miller CC.
Tudor EL, et al.
J Biol Chem. 2005 Oct 14;280(41):34735-40. doi: 10.1074/jbc.M506216200. Epub 2005 Jul 26.
J Biol Chem. 2005.
PMID: 16049005
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