New Pyrrolizidine Alkaloids and Glycosides from Anchusa strigosa

Planta Med. 2003 Sep;69(9):835-41. doi: 10.1055/s-2003-43202.

Abstract

Six new pyrrolizidine alkaloids, a new carboxylic acid, a new phenolic and a new oleanane glycoside, together with the known compounds 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyltetrahydrofuran 4'-O-beta-D-glucopyranoside, rosmarinic acid, caffeic acid, tormentic acid 28-O-beta- D-glucopyranoside, euscaphic acid 28-O-beta-D-glucopyranoside, euscaphic acid, and allantoin were isolated from Anchusa strigosa roots. Their structures were established by high resolution NMR, MS, elemental analysis, and chemical reactions.

MeSH terms

  • Boraginaceae*
  • Glycosides / administration & dosage
  • Glycosides / chemistry
  • Glycosides / pharmacology*
  • Humans
  • Magnetic Resonance Spectroscopy
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Roots
  • Pyrrolizidine Alkaloids / administration & dosage
  • Pyrrolizidine Alkaloids / chemistry
  • Pyrrolizidine Alkaloids / pharmacology*

Substances

  • Glycosides
  • Plant Extracts
  • Pyrrolizidine Alkaloids