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HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins: potential clinical implications regarding the insulin resistance of HIV-1-infected patients.
Diabetes. 2005 Jan;54(1):23-31. doi: 10.2337/diabetes.54.1.23.
Diabetes. 2005.
PMID: 15616007
Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?
Kino T, Chrousos GP.
Kino T, et al.
Ann N Y Acad Sci. 2004 Jun;1024:153-67. doi: 10.1196/annals.1321.013.
Ann N Y Acad Sci. 2004.
PMID: 15265780
Review.
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