The cognitive burden of multiple sclerosis in children

Neurology. 2005 Mar 8;64(5):891-4. doi: 10.1212/01.WNL.0000152896.35341.51.

Abstract

Little is known about the cognitive sequelae of pediatric-onset multiple sclerosis (MS). Ten pediatric patients with MS were evaluated using a comprehensive neuropsychological battery. Neuropsychological deficits were identified on measures of general cognition, language, visuomotor integration, and verbal and visual memory. Cognitive impairment occurs in children with MS, and those with longer disease duration and younger age at MS onset appear to be at greatest risk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Age of Onset
  • Brain / pathology
  • Brain / physiopathology*
  • Canada
  • Child
  • Cognition Disorders / diagnosis
  • Cognition Disorders / etiology*
  • Cognition Disorders / psychology*
  • Cohort Studies
  • Disability Evaluation
  • Disease Progression
  • Female
  • Humans
  • Immunologic Factors / therapeutic use
  • Male
  • Multiple Sclerosis / complications*
  • Multiple Sclerosis / physiopathology
  • Multiple Sclerosis / psychology*
  • Nerve Fibers, Myelinated / pathology
  • Neuropsychological Tests
  • Pilot Projects
  • Predictive Value of Tests

Substances

  • Immunologic Factors