Florfenicol resistance gene floR is part of a novel transposon

Antimicrob Agents Chemother. 2005 May;49(5):2106-8. doi: 10.1128/AAC.49.5.2106-2108.2005.

Abstract

The florfenicol/chloramphenicol resistance gene floR was found to be part of the novel 4,284-bp transposon TnfloR from Escherichia coli. TnfloR consists of the gene floR, a putative regulatory gene, and the transposase gene tnpA. A circular form of TnfloR was detected and suggested the potential mobility of this transposon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Chloramphenicol Resistance / genetics*
  • DNA Transposable Elements / genetics*
  • DNA, Circular / genetics
  • Escherichia coli / drug effects*
  • Escherichia coli / genetics*
  • Escherichia coli Proteins / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Thiamphenicol / analogs & derivatives*
  • Thiamphenicol / pharmacology*

Substances

  • Anti-Bacterial Agents
  • DNA Transposable Elements
  • DNA, Circular
  • Escherichia coli Proteins
  • FloR protein, E coli
  • florfenicol
  • Thiamphenicol