Purpose of review: Mitomycin-C is an antimetabolite that has seen increased use in ophthalmology over the past several decades. From glaucoma surgery to the management of various corneal disorders, mitomycin-C seems to be a viable tool in the management of scar and haze formation.
Recent findings: With the constant evolution of refractive surgery, mitomycin-C has come to the forefront as a modulator of corneal wound healing after excimer laser surface ablation.
Summary: This article will describe the various indications, techniques, and current trends of mitomycin-C application in corneal refractive surgery.