Abstract
The ketogenic diet is often effective for intractable epilepsy, but many patients have trouble complying with the strict regimen. The authors tested an alternative diet regimen, a low-glycemic-index treatment, with more liberal total carbohydrate intake but restricted to foods that produce relatively little increase in blood glucose (glycemic index < 50). Ten of 20 patients treated with this regimen experienced a greater than 90% reduction in seizure frequency.
MeSH terms
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Acidosis, Lactic / etiology
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Acidosis, Lactic / physiopathology
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Anticonvulsants / therapeutic use
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Blood Glucose / metabolism*
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Brain / metabolism
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Brain / physiopathology
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Dietary Fats / therapeutic use
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Energy Metabolism / physiology
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Epilepsy / diet therapy*
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Epilepsy / metabolism
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Epilepsy / physiopathology
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Food, Formulated / standards*
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Glycemic Index / physiology*
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Humans
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Ketones / blood*
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Patient Compliance
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Psychology
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Treatment Outcome
Substances
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Anticonvulsants
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Blood Glucose
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Dietary Fats
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Ketones