Socio-demographic and geographic indicators and distribution of tuberculosis in Hong Kong: a spatial analysis

Int J Tuberc Lung Dis. 2005 Dec;9(12):1320-6.

Abstract

Objective: To determine the socio-demographic and geographic indicators responsible for the distribution and transmission of tuberculosis (TB) in Hong Kong using geographical information system (GIS) technology.

Materials and methods: All patients with bacteriologically proven TB over a period of 3 years (May 1999-April 2002) residing within Hong Kong Island were studied. Molecular characterisation of their sputum isolates by IS6110-based restriction fragment length polymorphism (RFLP) technique was performed. Socio-demographic data were derived from the 2001 Hong Kong population census. Geographic coordinates of patients' addresses were linked to the GIS; large street block groups (LSBGs) were the units of analysis.

Results: Of 2387 patients with bacteriologically confirmed TB, 2332 had valid addresses distributed in 430 LSBGs in Hong Kong Island. Of the five socio-demographic indicators studied, significant correlations were found between the rate of TB in an LSBG and low educational attainment, elderly population and low-income household, but not population density or unemployment. The five socio-demographic indicators were not different between LSBG with clustered cases and those with unique cases.

Conclusion: Low educational attainment, old age and poverty were significant determinants of the rate of TB in different parts of Hong Kong, while none of the socio-demographic indicators was related to disease transmission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cluster Analysis
  • Female
  • Geographic Information Systems
  • Hong Kong / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Population Density
  • Risk Factors
  • Socioeconomic Factors
  • Topography, Medical
  • Tuberculosis / epidemiology*
  • Tuberculosis / etiology*