No abstract available
MeSH terms
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Animals
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Antineoplastic Agents / pharmacology
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Apoptosis
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Cell Differentiation
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Cell Proliferation
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Gene Expression Regulation, Developmental*
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Humans
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Mice
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Mice, Knockout
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Neurons / cytology
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Neurons / metabolism
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Phenotype
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Promoter Regions, Genetic / genetics
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Protein Processing, Post-Translational*
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Proto-Oncogene Proteins / antagonists & inhibitors
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Proto-Oncogene Proteins / genetics
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Proto-Oncogene Proteins / metabolism*
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Proto-Oncogene Proteins c-mdm2 / antagonists & inhibitors
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Proto-Oncogene Proteins c-mdm2 / genetics
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Proto-Oncogene Proteins c-mdm2 / metabolism*
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Stem Cells / cytology
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Stem Cells / metabolism
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Transcriptional Activation
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Tumor Suppressor Protein p53 / genetics
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Tumor Suppressor Protein p53 / metabolism*
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Ubiquitin / metabolism
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Ubiquitin-Protein Ligases / antagonists & inhibitors
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Ubiquitin-Protein Ligases / genetics
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Ubiquitin-Protein Ligases / metabolism*
Substances
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Antineoplastic Agents
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Mdm4 protein, mouse
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Proto-Oncogene Proteins
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Tumor Suppressor Protein p53
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Ubiquitin
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Mdm2 protein, mouse
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Proto-Oncogene Proteins c-mdm2
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Ubiquitin-Protein Ligases