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A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
Nat Cell Biol. 2006 Aug;8(8):894-6. doi: 10.1038/ncb1450. Epub 2006 Jul 9.
Nat Cell Biol. 2006.
PMID: 16829951
The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells.
Kirkin V, Cahuzac N, Guardiola-Serrano F, Huault S, Lückerath K, Friedmann E, Novac N, Wels WS, Martoglio B, Hueber AO, Zörnig M.
Kirkin V, et al.
Cell Death Differ. 2007 Sep;14(9):1678-87. doi: 10.1038/sj.cdd.4402175. Epub 2007 Jun 8.
Cell Death Differ. 2007.
PMID: 17557115
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