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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2006 | 1 |
2009 | 1 |
2011 | 1 |
2012 | 1 |
2014 | 2 |
2015 | 1 |
2024 | 0 |
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The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.
EMBO J. 2006 Aug 9;25(15):3556-64. doi: 10.1038/sj.emboj.7601241. Epub 2006 Jul 20.
EMBO J. 2006.
PMID: 16858395
Free PMC article.
A dimerization-dependent mechanism drives RAF catalytic activation.
Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M.
Rajakulendran T, et al.
Nature. 2009 Sep 24;461(7263):542-5. doi: 10.1038/nature08314. Epub 2009 Sep 2.
Nature. 2009.
PMID: 19727074
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Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.
Packer LM, Rana S, Hayward R, O'Hare T, Eide CA, Rebocho A, Heidorn S, Zabriskie MS, Niculescu-Duvaz I, Druker BJ, Springer C, Marais R.
Packer LM, et al.
Cancer Cell. 2011 Dec 13;20(6):715-27. doi: 10.1016/j.ccr.2011.11.004.
Cancer Cell. 2011.
PMID: 22169110
Free PMC article.
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Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.
Röring M, Herr R, Fiala GJ, Heilmann K, Braun S, Eisenhardt AE, Halbach S, Capper D, von Deimling A, Schamel WW, Saunders DN, Brummer T.
Röring M, et al.
EMBO J. 2012 May 30;31(11):2629-47. doi: 10.1038/emboj.2012.100. Epub 2012 Apr 17.
EMBO J. 2012.
PMID: 22510884
Free PMC article.
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Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling.
Haling JR, Sudhamsu J, Yen I, Sideris S, Sandoval W, Phung W, Bravo BJ, Giannetti AM, Peck A, Masselot A, Morales T, Smith D, Brandhuber BJ, Hymowitz SG, Malek S.
Haling JR, et al.
Cancer Cell. 2014 Sep 8;26(3):402-413. doi: 10.1016/j.ccr.2014.07.007. Epub 2014 Aug 21.
Cancer Cell. 2014.
PMID: 25155755
Free article.
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Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.
Thevakumaran N, Lavoie H, Critton DA, Tebben A, Marinier A, Sicheri F, Therrien M.
Thevakumaran N, et al.
Nat Struct Mol Biol. 2015 Jan;22(1):37-43. doi: 10.1038/nsmb.2924. Epub 2014 Dec 1.
Nat Struct Mol Biol. 2015.
PMID: 25437913
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