From vanilla to 28 flavors: multiple varieties of T regulatory cells

Ethan M Shevach

doi:10.1016/j.immuni.2006.08.003

From vanilla to 28 flavors: multiple varieties of T regulatory cells

Immunity. 2006 Aug;25(2):195-201. doi: 10.1016/j.immuni.2006.08.003.

Author

Ethan M Shevach¹

Affiliation

¹ Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. eshevach@niaid.nih.gov

PMID: 16920638
DOI: 10.1016/j.immuni.2006.08.003

Abstract

Numerous T cell subpopulations have now been claimed to exhibit regulatory activity. Shevach discusses the current understanding of the different subsets of T regulatory cells and provides a perspective on the current areas of uncertainly and controversy in the field.

MeSH terms

Adaptation, Biological / immunology
Animals
Antigens / immunology
CD8-Positive T-Lymphocytes / immunology
CD8-Positive T-Lymphocytes / metabolism
Cell Separation
Forkhead Transcription Factors / metabolism
Humans
Interleukin-10 / biosynthesis
T-Lymphocytes, Regulatory / classification*
T-Lymphocytes, Regulatory / immunology*
T-Lymphocytes, Regulatory / metabolism

Substances

Antigens
Forkhead Transcription Factors
Interleukin-10