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Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.
Mol Cell Biol. 2007 Feb;27(4):1380-93. doi: 10.1128/MCB.01608-06. Epub 2006 Dec 4.
Mol Cell Biol. 2007.
PMID: 17145773
Free PMC article.
Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
Sagara M, Kawasaki Y, Iemura SI, Natsume T, Takai Y, Akiyama T.
Sagara M, et al.
Oncogene. 2009 Mar 12;28(10):1357-65. doi: 10.1038/onc.2008.478. Epub 2009 Jan 19.
Oncogene. 2009.
PMID: 19151759
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