Abstract
Among 144 ciprofloxacin-resistant Escherichia coli isolated in Brazil, one (0.69%) QnrA1-producing isolate was detected. The qnrA1 gene was associated with ISCR1. The QnrA1 determinant was carried on a 41-kb conjugative plasmid, which also carried a FOX-type cephalosporinase encoding gene and a class 1 integron with the aadB and catB3 cassettes. This is the first report of a qnrA-carrying isolate in a Latin American country.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Ciprofloxacin / pharmacology*
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Conjugation, Genetic
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Drug Resistance, Bacterial / genetics*
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Escherichia coli / enzymology
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Escherichia coli Infections / microbiology
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Escherichia coli Proteins / physiology*
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Integrons / genetics
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Latin America / epidemiology
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Molecular Sequence Data
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Plasmids / genetics*
Substances
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Anti-Bacterial Agents
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Escherichia coli Proteins
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Qnr protein, E coli
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Ciprofloxacin
Associated data
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GENBANK/AM295980
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GENBANK/AM295981