Abstract
The vertebrate gut harbors a coevolved consortium of microbes that plays critical roles in the development and health of this organ. Here we discuss recent insights into the microbial-host molecular dialogs that shape the digestive tracts of the model vertebrates, mice and zebrafish, and consider the parallels between vertebrate-microbial mutualisms and the well-studied squid-Vibrio symbiosis.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Disease Models, Animal
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Homeostasis
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Humans
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Immunity, Innate
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Intestinal Mucosa / microbiology*
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Intestinal Mucosa / physiology*
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Mice
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Polysaccharides / metabolism
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Signal Transduction
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Symbiosis
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Vertebrates / microbiology*
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Vertebrates / physiology*
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Zebrafish / microbiology
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Zebrafish / physiology