Epigenetics: a landscape takes shape

Cell. 2007 Feb 23;128(4):635-8. doi: 10.1016/j.cell.2007.02.006.

Abstract

Epigenetics has recently evolved from a collection of diverse phenomena to a defined and far-reaching field of study. In this Essay, we examine the epistemology of epigenetics, provide a brief overview of underlying molecular mechanisms, and suggest future challenges for the field.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Cell Differentiation / genetics*
  • Cell Division / genetics*
  • Chromatin Assembly and Disassembly / genetics
  • DNA Methylation
  • Epigenesis, Genetic / genetics*
  • Gene Expression Regulation / genetics*
  • Histones / genetics
  • Histones / metabolism
  • Humans
  • RNA, Untranslated / genetics

Substances

  • Histones
  • RNA, Untranslated