Variable platelet response to aspirin and clopidogrel in atherothrombotic disease

MeSH terms

• Adenosine Diphosphate / physiology
• Anti-Inflammatory Agents, Non-Steroidal / adverse effects
• Anti-Inflammatory Agents, Non-Steroidal / pharmacology
• Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
• Aspirin / adverse effects
• Aspirin / pharmacology*
• Aspirin / therapeutic use
• Atherosclerosis / blood
• Atherosclerosis / drug therapy*
• Biomarkers
• Biotransformation / genetics
• Blood Coagulation Tests
• Blood Platelets / drug effects*
• Blood Platelets / metabolism
• Cardiovascular Diseases / prevention & control
• Clopidogrel
• Cyclooxygenase 1 / physiology
• Cyclooxygenase Inhibitors / adverse effects
• Cyclooxygenase Inhibitors / pharmacology
• Cyclooxygenase Inhibitors / therapeutic use
• Drug Interactions
• Drug Resistance / genetics
• Hemorrhage / chemically induced
• Humans
• Platelet Activation / drug effects*
• Platelet Activation / physiology
• Platelet Aggregation Inhibitors / adverse effects
• Platelet Aggregation Inhibitors / pharmacology*
• Platelet Aggregation Inhibitors / therapeutic use
• Platelet Function Tests
• Prospective Studies
• Randomized Controlled Trials as Topic
• Receptors, Purinergic P2 / drug effects
• Receptors, Purinergic P2 / physiology
• Receptors, Purinergic P2Y1
• Receptors, Purinergic P2Y12
• Thrombosis / blood
• Thrombosis / drug therapy*
• Thromboxane A2 / physiology
• Thromboxane B2 / analogs & derivatives
• Thromboxane B2 / urine
• Ticlopidine / adverse effects
• Ticlopidine / analogs & derivatives*
• Ticlopidine / pharmacology
• Ticlopidine / therapeutic use
• Treatment Failure