Evaluation of the effect of subgingival placement of chlorhexidine chips as an adjunct to scaling and root planing

J Periodontol. 2007 Jun;78(6):997-1001. doi: 10.1902/jop.2007.060122.

Abstract

Background: The purpose of this 9-month study was to compare the effect of scaling and root planing alone (control) to that of scaling and root planing plus application of chlorhexidine chips (test).

Methods: Twenty-six subjects having two non-adjacent sites in non-molar teeth with probing depth > or =5 mm and bleeding on probing participated in this split-mouth trial. At baseline, the patients received full-mouth scaling and root planing followed by placement of chlorhexidine chips secured by cyanoacrylate at test sites and placement of cyanoacrylate alone at control sites. Test sites still > or =5 mm deep at 3 and 6 months were retreated with renewed chlorhexidine chip application. Recordings of bleeding on probing, probing depths, and clinical attachment levels were performed at baseline, after 6 weeks, and after 3, 6, and 9 months.

Results: Improvements of bleeding scores, probing depths and clinical attachment levels were observed for both test and control sites at 6 weeks compared to baseline. Subsequently, all three measurements remained comparatively stable throughout the study. No differences in improvements were found comparing test and control sites.

Conclusion: This study failed to observe any adjunctive effect of subgingival placement of chlorhexidine chips after scaling and root planing.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents, Local / administration & dosage*
  • Chlorhexidine / administration & dosage*
  • Dental Scaling*
  • Drug Implants
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Periodontal Attachment Loss / drug therapy
  • Periodontal Diseases / drug therapy*
  • Periodontal Index
  • Periodontal Pocket / drug therapy
  • Root Planing*
  • Single-Blind Method

Substances

  • Anti-Infective Agents, Local
  • Drug Implants
  • Chlorhexidine