Chaperoning cell death: a critical dual role for Hsp90 in small-cell lung cancer

Nat Chem Biol. 2007 Aug;3(8):455-7. doi: 10.1038/nchembio0807-455.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Apoptosis
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / genetics
  • Carcinoma, Small Cell / metabolism*
  • Gene Expression Regulation, Neoplastic*
  • HSP70 Heat-Shock Proteins / metabolism
  • HSP90 Heat-Shock Proteins / metabolism
  • HSP90 Heat-Shock Proteins / physiology*
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics
  • Lung Neoplasms / metabolism*
  • Models, Biological
  • Models, Chemical
  • Molecular Chaperones / metabolism
  • Proto-Oncogene Proteins c-bcl-2 / metabolism

Substances

  • HSP70 Heat-Shock Proteins
  • HSP90 Heat-Shock Proteins
  • Molecular Chaperones
  • Proto-Oncogene Proteins c-bcl-2