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(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1.
Mol Cancer Res. 2007 Aug;5(8):801-12. doi: 10.1158/1541-7786.MCR-07-0100.
Mol Cancer Res. 2007.
PMID: 17699106
Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing.
Sridevi P, Alexander H, Laviad EL, Min J, Mesika A, Hannink M, Futerman AH, Alexander S.
Sridevi P, et al.
Exp Cell Res. 2010 Jan 1;316(1):78-91. doi: 10.1016/j.yexcr.2009.09.027. Epub 2009 Oct 2.
Exp Cell Res. 2010.
PMID: 19800881
Free PMC article.
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Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy.
Vanni N, Fruscione F, Ferlazzo E, Striano P, Robbiano A, Traverso M, Sander T, Falace A, Gazzerro E, Bramanti P, Bielawski J, Fassio A, Minetti C, Genton P, Zara F.
Vanni N, et al.
Ann Neurol. 2014 Aug;76(2):206-12. doi: 10.1002/ana.24170. Epub 2014 May 20.
Ann Neurol. 2014.
PMID: 24782409
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