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Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.
Nat Immunol. 2009 Aug;10(8):831-9. doi: 10.1038/ni.1769. Epub 2009 Jul 13.
Nat Immunol. 2009.
PMID: 19597497
Free PMC article.
Themis, a T cell-specific protein important for late thymocyte development.
Lesourne R, Uehara S, Lee J, Song KD, Li L, Pinkhasov J, Zhang Y, Weng NP, Wildt KF, Wang L, Bosselut R, Love PE.
Lesourne R, et al.
Nat Immunol. 2009 Aug;10(8):840-7. doi: 10.1038/ni.1768. Epub 2009 Jul 13.
Nat Immunol. 2009.
PMID: 19597498
Free PMC article.
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Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.
Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, Gascoigne NR.
Fu G, et al.
Nat Immunol. 2009 Aug;10(8):848-56. doi: 10.1038/ni.1766. Epub 2009 Jul 13.
Nat Immunol. 2009.
PMID: 19597499
Free PMC article.
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Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.
Patrick MS, Oda H, Hayakawa K, Sato Y, Eshima K, Kirikae T, Iemura S, Shirai M, Abe T, Natsume T, Sasazuki T, Suzuki H.
Patrick MS, et al.
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16345-50. doi: 10.1073/pnas.0908593106. Epub 2009 Sep 14.
Proc Natl Acad Sci U S A. 2009.
PMID: 19805304
Free PMC article.
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