Abstract
Two murine homologs of the Drosophila Krüppel gene, a member of the gap class of developmental control genes that encode a protein with zinc fingers, were mapped to mouse chromosomes 8 and 11 by using somatic cell hybrids and an interspecific backcross. Surprisingly, both genes were closely linked to two previously mapped, Krüppel-related zinc finger protein genes, suggesting that they are part of gene complexes.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Chromosome Mapping
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Cricetinae
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Cricetulus / genetics
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Drosophila melanogaster / genetics
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Embryonic and Fetal Development / genetics
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Genes
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Genes, Homeobox
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Genes, Regulator
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Hybrid Cells / chemistry
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Mice / genetics*
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Mice, Inbred BALB C / genetics
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Multigene Family*
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Muridae / genetics
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Sequence Homology, Nucleic Acid
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Species Specificity
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Zinc Fingers / genetics*