Purpose of investigation: To evaluate the effect of pregnancy on uterine myoma and the effect of uterine myoma on the pregnancy prospectively.
Methods: Prospective evaluation of 19 pregnant women with uterine myomas was done between January 2005 and February 2008 at the Gynecology and Obstetrics Department Gaziantep University. The number and changes in size of the uterine myomas during pregnancy, and perinatal complications were documented.
Results: Totally 37 fibroids in 19 pregnant women were observed. Neither enlargement of myomas nor serious perinatal complications were observed.
Conclusion: We suggest that in contrast with the general opinion there is not much effect of pregnancy on uterine myoma size, and most cases are not affected by the presence of uterine fibroids resulting in severe perinatal complications. Expectant management may be an option for uterine myomas determined before gestation.