Tools to tackle protein acetylation

Chem Biol. 2009 Oct 30;16(10):1027-9. doi: 10.1016/j.chembiol.2009.10.002.

Abstract

In the recent issue of Molecular Cell, Neumann et al. dissect the effect of H3K56 acetylation on chromatin structure using a novel method for generation of acetylated proteins. This is a valuable addition to the toolkit for those interested in unraveling how posttranslational modifications regulate protein function.

MeSH terms

  • Acetylation
  • Chromatin / chemistry
  • Chromatin / metabolism
  • Histone Deacetylases / metabolism
  • Histones / metabolism*
  • Protein Processing, Post-Translational

Substances

  • Chromatin
  • Histones
  • Histone Deacetylases