Abstract
A Trichoderma harzianum strain, isolated from composted hardwood bark in Western Australia, was found to produce a metabolite with antifungal and plant growth promoting activity. The structure and absolute configuration of the fungal compound, harzianic acid (1), were determined by X-ray diffraction studies. Harzianic acid showed antibiotic activity against Pythium irregulare, Sclerotinia sclerotiorum, and Rhizoctonia solani. A plant growth promotion effect was observed at low concentrations of 1.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / chemistry
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Antifungal Agents / isolation & purification*
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Antifungal Agents / pharmacology*
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Ascomycota / drug effects
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Crystallography, X-Ray
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Hydroxybutyrates / chemistry
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Hydroxybutyrates / isolation & purification
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Hydroxybutyrates / pharmacology
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Microbial Sensitivity Tests
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Molecular Conformation
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Molecular Structure
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Plant Bark / chemistry
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Plant Growth Regulators / chemistry
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Plant Growth Regulators / isolation & purification*
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Plant Growth Regulators / pharmacology*
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Pyrroles / chemistry
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Pyrroles / isolation & purification
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Pyrroles / pharmacology
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Pythium / drug effects
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Rhizoctonia / drug effects*
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Trichoderma / chemistry*
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Western Australia
Substances
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Antifungal Agents
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Hydroxybutyrates
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Plant Growth Regulators
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Pyrroles
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harzianic acid