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HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.
J Biol Chem. 2010 Oct 1;285(40):30884-905. doi: 10.1074/jbc.M110.135947. Epub 2010 Jul 9.
J Biol Chem. 2010.
PMID: 20622010
Free PMC article.
HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.
Schaefer MR, Wonderlich ER, Roeth JF, Leonard JA, Collins KL.
Schaefer MR, et al.
PLoS Pathog. 2008 Aug 22;4(8):e1000131. doi: 10.1371/journal.ppat.1000131.
PLoS Pathog. 2008.
PMID: 18725938
Free PMC article.
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