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HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.
J Biol Chem. 2010 Oct 1;285(40):30884-905. doi: 10.1074/jbc.M110.135947. Epub 2010 Jul 9.
J Biol Chem. 2010.
PMID: 20622010
Free PMC article.
Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway.
daSilva LL, Sougrat R, Burgos PV, Janvier K, Mattera R, Bonifacino JS.
daSilva LL, et al.
J Virol. 2009 Jul;83(13):6578-90. doi: 10.1128/JVI.00548-09. Epub 2009 Apr 29.
J Virol. 2009.
PMID: 19403684
Free PMC article.
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