ATDB 2.0: A database integrated toxin-ion channel interaction data

Quanze He; Wenjun Han; Quanyuan He; Linju Huo; Jingjing Zhang; Yong Lin; Ping Chen; Songping Liang

doi:10.1016/j.toxicon.2010.05.013

ATDB 2.0: A database integrated toxin-ion channel interaction data

Toxicon. 2010 Sep 15;56(4):644-7. doi: 10.1016/j.toxicon.2010.05.013.

Authors

Quanze He¹, Wenjun Han, Quanyuan He, Linju Huo, Jingjing Zhang, Yong Lin, Ping Chen, Songping Liang

Affiliation

¹ The Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, PR China.

PMID: 20677374
DOI: 10.1016/j.toxicon.2010.05.013

Abstract

We have developed an updated version of the Animal Toxin Database (ATDB 2.0) that provides a new bioinformatics resource for analyzing toxin-channel (T-C) interactions. Data on more than 54,000 T-C interactions, including 9193 high-confidence interactions, has been extracted, formatted and mapped to toxin and ion channel databases. The interaction data can be accessed easily through a new network browser on the website at http://protchem.hunnu.edu.cn/toxin. This resource may be useful for sequence pattern recognition and prediction of the function of new toxins.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computational Biology
Databases, Factual*
Ion Channels / chemistry*
Protein Structure, Tertiary
Sequence Analysis, Protein
Toxins, Biological / chemistry*
User-Computer Interface

Substances

Ion Channels
Toxins, Biological