Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas

Haematologica. 2011 Feb;96(2):343-6. doi: 10.3324/haematol.2010.031484. Epub 2010 Nov 25.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anaplastic Lymphoma Kinase
  • Chromosomes, Human, Pair 2 / genetics
  • Chromosomes, Human, Pair 4 / genetics
  • Humans
  • In Situ Hybridization, Fluorescence
  • Lymphoma, Large B-Cell, Diffuse / genetics*
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Male
  • Oncogene Proteins, Fusion / genetics*
  • Prognosis
  • RNA, Messenger / genetics
  • RNA, Neoplasm / genetics
  • Receptor Protein-Tyrosine Kinases / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Translocation, Genetic / genetics
  • Vesicular Transport Proteins / genetics*

Substances

  • Oncogene Proteins, Fusion
  • RNA, Messenger
  • RNA, Neoplasm
  • SEC31A protein, human
  • Vesicular Transport Proteins
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases