Steroids with aromatic A-rings from the Hainan soft coral Dendronephthya studeri Ridley

J Nat Prod. 2011 Feb 25;74(2):175-80. doi: 10.1021/np100562n. Epub 2010 Dec 30.

Abstract

Eight new marine steroids, characterized by either the presence of an aromatic ring or a cross-conjugated dienone system in ring A, were isolated from the Hainan soft coral Dendronephthya studeri Ridley. Their structures were elucidated on the basis of detailed spectroscopic analysis and by comparison of their NMR data with those reported in the literature.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anthozoa / chemistry*
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Drug Screening Assays, Antitumor
  • HL-60 Cells
  • Humans
  • Leukemia P388
  • Mice
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Steroids / chemistry*
  • Steroids / isolation & purification*
  • Steroids / pharmacology

Substances

  • Antineoplastic Agents
  • Steroids
  • methyl spongoate