Equine-derived bone substitutes in orthopedics and traumatology: authors' experience

Minerva Chir. 2011 Feb;66(1):63-72.

Abstract

Aim: To evaluate the use of equine-derived bone grafts in the treatment of bone loss in a heterogeneous clinical case series.

Methods: The study population was 48 patients (29 males and 19 females; mean age, 49 years; range, 9-84); the orthopedic defect site was located on the right side in 22 and on the left side in 26 cases. The graft material was antigen-free equine-derived collagen bone cleaned with an enzymatic treatment.

Results: Clinical and radiographic healing times were virtually similar; graft osseointegration needed from two to three months longer to heal.

Conclusion: The outcome after grafting with an equine-derived bone substitute was satisfactory. Further study is needed to demonstrate its statistically significant effectiveness in the treatment of orthopedic defects like those in this series.

Publication types

  • Evaluation Study
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Bone Substitutes / therapeutic use*
  • Bone Transplantation*
  • Child
  • Female
  • Fracture Fixation, Internal / methods*
  • Horses
  • Humans
  • Male
  • Middle Aged
  • Orthopedics / methods*
  • Osseointegration
  • Retrospective Studies
  • Transplantation, Heterologous*
  • Treatment Outcome
  • Young Adult

Substances

  • Bone Substitutes