Citicoline: pharmacological and clinical review, 2010 update

Rev Neurol. 2011 Mar 14:52 Suppl 2:S1-S62.
[Article in English, Spanish]

Abstract

This review is based on the previous one published in 2006 -Secades JJ, Lorenzo JL. Citicoline: pharmacological and clinical review, 2006 update. Methods Find Exp Clin Pharmacol 2006; 28 (Suppl B): S1-56-, incorporating the new references until now, having all the information available to facilitate the access to the informacion in one document. This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.

Publication types

  • Review

MeSH terms

  • Brain Injuries / drug therapy
  • Brain Ischemia / drug therapy
  • Cerebrovascular Disorders / drug therapy
  • Clinical Trials as Topic
  • Cognition Disorders / drug therapy
  • Cytidine Diphosphate Choline / pharmacokinetics
  • Cytidine Diphosphate Choline / pharmacology*
  • Cytidine Diphosphate Choline / therapeutic use*
  • Cytidine Diphosphate Choline / toxicity
  • Humans
  • Learning / drug effects
  • Memory / drug effects
  • Stroke / drug therapy
  • Synaptic Transmission / drug effects

Substances

  • Cytidine Diphosphate Choline