Hepatic lipomas and steatosis: an association beyond chance

Eur J Radiol. 2012 Apr;81(4):e491-4. doi: 10.1016/j.ejrad.2011.06.018. Epub 2011 Jul 12.

Abstract

Objective: To determine if hepatic lipomas have a higher prevalence of liver steatosis than other benign hepatic lesions.

Materials and methods: Ninety-two benign hepatic lesions were analyzed with magnetic resonance (MR) imaging. There were 6 lipomas and 86 benign non-lipomatous lesions, including 55 hemangiomas, 23 focal nodular hyperplasias (FNH) and 8 adenomas. All studies included a chemical shift T1-weighted sequence (in-phase and opposed-phase) in order to evaluate the presence of steatosis.

Results: A statistically significant relationship (Fischer's Exact Test, p=0.019) between hepatic lipomas and steatosis was demonstrated. Fifty percent of hepatic lipomas associated steatosis, while this association was present in only 9% of the non-lipomatous lesions.

Conclusion: Lipomas have a significantly greater association with steatosis when compared to nonlipomatous lesions. This relationship may be related to a common insuline resistance mechanism.

MeSH terms

  • Adult
  • Aged
  • Causality
  • Comorbidity
  • Fatty Liver / epidemiology*
  • Fatty Liver / pathology*
  • Female
  • Humans
  • Lipoma / epidemiology*
  • Lipoma / pathology*
  • Liver Neoplasms / epidemiology*
  • Liver Neoplasms / pathology*
  • Magnetic Resonance Imaging / statistics & numerical data*
  • Male
  • Middle Aged
  • Prevalence
  • Reproducibility of Results
  • Risk Assessment
  • Risk Factors
  • Sensitivity and Specificity
  • Spain / epidemiology