AMPA: an automated web server for prediction of protein antimicrobial regions

Bioinformatics. 2012 Jan 1;28(1):130-1. doi: 10.1093/bioinformatics/btr604. Epub 2011 Nov 3.

Abstract

Summary: AMPA is a web application for assessing the antimicrobial domains of proteins, with a focus on the design on new antimicrobial drugs. The application provides fast discovery of antimicrobial patterns in proteins that can be used to develop new peptide-based drugs against pathogens. Results are shown in a user-friendly graphical interface and can be downloaded as raw data for later examination.

Availability: AMPA is freely available on the web at http://tcoffee.crg.cat/apps/ampa. The source code is also available in the web.

Contact: marc.torrent@upf.edu; david.andreu@upf.edu

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Anti-Infective Agents / chemistry*
  • Antimicrobial Cationic Peptides / chemistry
  • Internet
  • Peptides / chemistry*
  • Programming Languages
  • Protein Structure, Tertiary
  • Software

Substances

  • Anti-Infective Agents
  • Antimicrobial Cationic Peptides
  • Peptides