Abstract
In Asia, bla(KPC) detection has been limited to East Asia and not yet seen in Southeast Asia. We report four bla(KPC-2)-containing Klebsiella pneumoniae isolates from two different hospitals in Singapore. All isolates belonged to strain type 11 (ST11) and were indistinguishable by pulsed-field gel electrophoresis (PFGE). bla(KPC-2) was located on nonconjugative plasmids and flanked by mobile genetic structures composed of a partial Tn4401 transposon and a Tn3-based transposon which previously have been described only in Chinese isolates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cluster Analysis
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DNA Transposable Elements
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DNA, Bacterial / genetics
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Electrophoresis, Gel, Pulsed-Field
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Genotype
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Hospitals
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Humans
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / classification
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification
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Molecular Typing
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Plasmids
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Singapore
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beta-Lactamases / genetics*
Substances
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DNA Transposable Elements
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DNA, Bacterial
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beta-Lactamases
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beta-lactamase KPC-2, Klebsiella pneumoniae