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ATR maintains select progenitors during nervous system development.
EMBO J. 2012 Mar 7;31(5):1177-89. doi: 10.1038/emboj.2011.493. Epub 2012 Jan 20.
EMBO J. 2012.
PMID: 22266795
Free PMC article.
An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.
Zhou ZW, Liu C, Li TL, Bruhn C, Krueger A, Min W, Wang ZQ, Carr AM.
Zhou ZW, et al.
PLoS Genet. 2013;9(8):e1003702. doi: 10.1371/journal.pgen.1003702. Epub 2013 Aug 8.
PLoS Genet. 2013.
PMID: 23950734
Free PMC article.
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TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells.
Jeon Y, Ko E, Lee KY, Ko MJ, Park SY, Kang J, Jeon CH, Lee H, Hwang DS.
Jeon Y, et al.
J Biol Chem. 2011 Feb 18;286(7):5414-22. doi: 10.1074/jbc.M110.189704. Epub 2010 Dec 13.
J Biol Chem. 2011.
PMID: 21149450
Free PMC article.
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