Interstitial cystitis: diagnosis and management

Eur J Obstet Gynecol Reprod Biol. 2012 Mar;161(1):1-7. doi: 10.1016/j.ejogrb.2011.12.014. Epub 2012 Feb 4.

Abstract

Interstitial cystitis/painful bladder syndrome is a chronic condition that causes debilitating bladder pain which can be associated with urgency, frequency and nocturia. Its cause is not clear and it is still a disease diagnosed by exclusion. Oral or intravesical therapies are the main stay of treatment whilst surgical procedures are reserved for refractory cases. This condition usually warrants a multidisciplinary approach for optimum outcome. This article gives an overview of the changes in definition, aetiopathogenesis and available treatments.

Publication types

  • Review

MeSH terms

  • Administration, Intravesical
  • Analgesics / therapeutic use
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Botulinum Toxins / administration & dosage
  • Cystitis, Interstitial / diagnosis*
  • Cystitis, Interstitial / surgery
  • Cystitis, Interstitial / therapy*
  • Dimethyl Sulfoxide / administration & dosage
  • Diterpenes / administration & dosage
  • Female
  • Heparin / administration & dosage
  • Humans
  • Male
  • Pentosan Sulfuric Polyester / therapeutic use

Substances

  • Analgesics
  • Antidepressive Agents, Tricyclic
  • Diterpenes
  • Pentosan Sulfuric Polyester
  • Heparin
  • resiniferatoxin
  • Botulinum Toxins
  • Dimethyl Sulfoxide