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The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult.
Cell Rep. 2012 Jul 26;2(1):111-23. doi: 10.1016/j.celrep.2012.06.003. Epub 2012 Jun 28.
Cell Rep. 2012.
PMID: 22840402
Free PMC article.
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development.
Eißmann M, Gutschner T, Hämmerle M, Günther S, Caudron-Herger M, Groß M, Schirmacher P, Rippe K, Braun T, Zörnig M, Diederichs S.
Eißmann M, et al.
RNA Biol. 2012 Aug;9(8):1076-87. doi: 10.4161/rna.21089. Epub 2012 Aug 1.
RNA Biol. 2012.
PMID: 22858678
Free PMC article.
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Malat1 is not an essential component of nuclear speckles in mice.
Nakagawa S, Ip JY, Shioi G, Tripathi V, Zong X, Hirose T, Prasanth KV.
Nakagawa S, et al.
RNA. 2012 Aug;18(8):1487-99. doi: 10.1261/rna.033217.112. Epub 2012 Jun 20.
RNA. 2012.
PMID: 22718948
Free PMC article.
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