Complete genome sequences of two Helicobacter pylori bacteriophages isolated from Japanese patients

J Virol. 2012 Oct;86(20):11400-1. doi: 10.1128/JVI.01767-12.

Abstract

Helicobacter pylori causes peptic ulcers and gastric cancer, which lead to significantly higher morbidity in Japan than elsewhere in the world. As bacteriophage (phage) and host bacteria coevolve, the study of H. pylori phages is important to extend understanding of the evolution and pathogenesis of H. pylori. Here we report two complete genome sequences of H. pylori phages KHP30 and KHP40, which were released spontaneously from the most pathogenic East Asian-type isolates from Japanese patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriophages / genetics*
  • Bacteriophages / isolation & purification
  • Base Sequence
  • DNA, Viral / analysis
  • DNA, Viral / genetics
  • Evolution, Molecular
  • Genome, Viral*
  • Helicobacter pylori / virology*
  • Humans
  • Japan
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA, Viral

Associated data

  • GENBANK/AB647160
  • GENBANK/AB731695