Management of urinary tract infections from multidrug-resistant organisms

Kalpana Gupta; Nahid Bhadelia

doi:10.1016/j.idc.2013.10.002

Management of urinary tract infections from multidrug-resistant organisms

Infect Dis Clin North Am. 2014 Mar;28(1):49-59. doi: 10.1016/j.idc.2013.10.002. Epub 2013 Dec 8.

Authors

Kalpana Gupta¹, Nahid Bhadelia²

Affiliations

¹ Infectious Diseases, VA Boston HCS, 1400 VFW Parkway, West Roxbury, MA 02312, USA; Infectious Diseases, Boston University School of Medicine, Dowling 3 North Room 3104, Boston, MA 02115, USA. Electronic address: kalpana.gupta@va.gov.
² Section of Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Dowling 3 North Room 3104, Boston, MA 02115, USA.

PMID: 24484574
DOI: 10.1016/j.idc.2013.10.002

Abstract

Antibiotic resistance worsens clinical outcomes and, in some cases, significantly impacts the clinical management of urinary tract infections in the outpatient setting. This article presents the prevalence and mechanism of relevant antimicrobial resistance patterns encountered among uropathogens, and discusses the efficacy of antibiotic regimens and novel therapies in treating commonly encountered multidrug-resistant organisms.

Keywords: Carbapenem-resistant Enterobacteriaceae; Cystitis; Extended-spectrum β-lactamases; Multidrug-resistant organisms; Vancomycin-resistant Enterococcus.

Published by Elsevier Inc.

Publication types

Review

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Disease Management
Drug Resistance, Multiple, Bacterial*
Drug Therapy, Combination
Enterobacteriaceae Infections / drug therapy
Enterobacteriaceae Infections / microbiology
Escherichia coli Infections / drug therapy
Escherichia coli Infections / microbiology
Humans
Staphylococcal Infections / drug therapy
Staphylococcal Infections / microbiology
Urinary Tract Infections* / drug therapy
Urinary Tract Infections* / microbiology

Substances

Anti-Bacterial Agents