Aplasia cutis congenita: approach to evaluation and management

Dermatol Ther. 2013 Nov-Dec;26(6):439-44. doi: 10.1111/dth.12106.

Abstract

Aplasia cutis congenita (ACC) refers to any condition in which there is absence of skin at birth. This can be isolated ACC occurring on the scalp, with or without underlying ectopic neural tissue, or ACC can be associated with other conditions such as Adams-Oliver syndrome or epidermolysis bullosa. We discuss the different types of ACC and associated anomalies along with an approach to diagnosis and management.

Keywords: Adams–Oliver syndrome; aplasia cutis congenita.

MeSH terms

  • Diagnosis, Differential
  • Ectodermal Dysplasia / diagnosis*
  • Ectodermal Dysplasia / pathology
  • Ectodermal Dysplasia / therapy*
  • Female
  • Herpes Simplex / diagnosis
  • Humans
  • Limb Deformities, Congenital / diagnosis
  • Nevus, Sebaceous of Jadassohn / diagnosis
  • Pregnancy
  • Pregnancy, Twin
  • Scalp Dermatoses / congenital
  • Scalp Dermatoses / diagnosis

Supplementary concepts

  • Adams Oliver syndrome