Complete genome characterization of mosavirus (family Picornaviridae) identified in droppings of a European roller (Coracias garrulus) in Hungary

Arch Virol. 2014 Oct;159(10):2723-9. doi: 10.1007/s00705-014-2113-4. Epub 2014 May 14.

Abstract

Mosavirus (mosavirus A1, M-7/2010/USA, JF973687), a novel picornavirus, was found in a canyon mouse (Peromyscus crinitus) in the USA in 2010. It represents a novel species (Mosavirus A) in a novel genus (Mosavirus) in the family Picornaviridae. In this study, the first complete genome sequence of another mosavirus, SZAL6-MoV/2011/HUN (KF958461), was determined from one out of 18 fecal samples from an Afro-Palearctic migratory bird, the European roller (Coracias garrulus). The complete genome of SZAL6-MoV/2011/HUN is 8385 nt long (from poly(C) tract to poly(A) tail), contains a 646-nt-long 5'UTR that forms a type II IRES, and encodes a potential 2550-aa-long polyprotein precursor including an aphthovirus-like L(pro)-proteinase, a small aphthovirus-like 2A(NPG↓P), and two 3B(VPg) proteins. SZAL6-MoV/2011/HUN has 67 %, 74 %, and 76 % aa sequence identity in the P1, P2, and P3 region, respectively, to M-7/2010/USA and represents a second mosavirus type, mosavirus A2.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5' Untranslated Regions
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Birds / virology*
  • DNA, Viral / analysis
  • DNA, Viral / genetics
  • Feces / virology*
  • Genome, Viral / genetics*
  • Hungary
  • Molecular Sequence Data
  • Open Reading Frames / genetics
  • Picornaviridae / classification
  • Picornaviridae / genetics*
  • RNA, Viral / genetics
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Viral Proteins / genetics*

Substances

  • 5' Untranslated Regions
  • DNA, Viral
  • RNA, Viral
  • Viral Proteins

Associated data

  • GENBANK/KF958461