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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.
Sci Transl Med. 2014.
PMID: 24990881
The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
Cheng-Hathaway PJ, Reed-Geaghan EG, Jay TR, Casali BT, Bemiller SM, Puntambekar SS, von Saucken VE, Williams RY, Karlo JC, Moutinho M, Xu G, Ransohoff RM, Lamb BT, Landreth GE.
Cheng-Hathaway PJ, et al.
Mol Neurodegener. 2018 Jun 1;13(1):29. doi: 10.1186/s13024-018-0262-8.
Mol Neurodegener. 2018.
PMID: 29859094
Free PMC article.
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