Lim mineralization protein-1 knockout mice have reduced spine trabecular bone density on microcomputed tomography due to decreased bone morphogenetic protein responsiveness

Neurosurgery. 2014 Aug:61 Suppl 1:182-6. doi: 10.1227/NEU.0000000000000414.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Bone Density / physiology*
  • Bone Morphogenetic Proteins / metabolism*
  • Calcification, Physiologic / physiology*
  • Cytoskeletal Proteins / genetics*
  • Disease Models, Animal*
  • Female
  • Intracellular Signaling Peptides and Proteins / genetics*
  • LIM Domain Proteins / genetics*
  • Mice
  • Mice, Knockout
  • Osteoporosis / genetics
  • Osteoporosis / metabolism
  • Spine / diagnostic imaging
  • X-Ray Microtomography

Substances

  • Bone Morphogenetic Proteins
  • Cytoskeletal Proteins
  • Intracellular Signaling Peptides and Proteins
  • LIM Domain Proteins
  • Pdlim7 protein, mouse