Abstract
We describe the metagenomics-derived feline enteric virome in the faeces of 25 cats from a single shelter in California. More than 90 % of the recognizable viral reads were related to mammalian viruses and the rest to bacterial viruses. Eight viral families were detected: Astroviridae, Coronaviridae, Parvoviridae, Circoviridae, Herpesviridae, Anelloviridae, Caliciviridae and Picobirnaviridae. Six previously known viruses were also identified: feline coronavirus type 1, felid herpes 1, feline calicivirus, feline norovirus, feline panleukopenia virus and picobirnavirus. Novel species of astroviruses and bocaviruses, and the first genome of a cyclovirus in a feline were characterized. The RNA-dependent RNA polymerase region from four highly divergent partial viral genomes in the order Picornavirales were sequenced. The detection of such a diverse collection of viruses shed within a single shelter suggested that such animals experience robust viral exposures. This study increases our understanding of the viral diversity in cats, facilitating future evaluation of their pathogenic and zoonotic potentials.
© 2014 The Authors.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Anelloviridae / genetics
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Anelloviridae / isolation & purification
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Animals
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Astroviridae / genetics
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Astroviridae / isolation & purification
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Bocavirus / genetics
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Bocavirus / isolation & purification
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Caliciviridae / genetics
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Caliciviridae / isolation & purification
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California
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Cats / virology*
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Circoviridae / genetics
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Circoviridae / isolation & purification
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Feces / virology
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Fishes / virology
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Genetic Variation
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Genome, Viral*
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Herpesviridae / genetics
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Herpesviridae / isolation & purification
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High-Throughput Nucleotide Sequencing
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Insect Viruses / genetics
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Metagenomics
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Molecular Sequence Data
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Parvoviridae / genetics
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Parvoviridae / isolation & purification
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Phylogeny
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Picobirnavirus / genetics
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Picobirnavirus / isolation & purification
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Plant Viruses / genetics
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RNA-Dependent RNA Polymerase / genetics
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Viral Proteins / genetics
Substances
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Viral Proteins
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RNA-Dependent RNA Polymerase
Associated data
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GENBANK/KM017736
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GENBANK/KM017737
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GENBANK/KM017738
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GENBANK/KM017739
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GENBANK/KM017740
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GENBANK/KM017741
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GENBANK/KM017742
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GENBANK/KM017743
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GENBANK/KM017744
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GENBANK/KM017745