A multicenter point-prevalence survey of antibiotic use in 13 Chinese hospitals

J Infect Public Health. 2015 Jan-Feb;8(1):55-61. doi: 10.1016/j.jiph.2014.07.001. Epub 2014 Aug 14.

Abstract

Background: The use of antibiotics is considered a major determinant of the development of resistance in organisms. This study assessed current patterns of antibiotic prescription and provides background for quality improvement in general hospitals in Hubei, China.

Methods: A point-prevalence study was performed in November 2008. All inpatients on the day of the survey were included in the analysis.

Results: On the day of the study, 6904 patients (56%) were receiving antibiotic therapy; the highest rate occurred in the ICU (90%), and the lowest occurred in the medical wards (39%). The most commonly used antibiotics were β-lactam antibiotics, including cephalosporins (40%) and piperacillin (19%), followed by fluoroquinolones (14%).

Conclusions: Our data indicated a high rate of antibiotic use in Chinese hospitals. These findings suggest important areas for intervention and the implementation of antibiotic stewardship policies in Chinese hospitals. A multi-faceted strategy should be implemented at the national level in China and should include education, regulation, and greater financial support from the government.

Keywords: Antibiotic use; China; Point-prevalence survey.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • China / epidemiology
  • Drug Prescriptions / statistics & numerical data*
  • Drug Resistance, Microbial
  • Drug Utilization / statistics & numerical data*
  • Female
  • Health Surveys
  • Hospitals / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Quality Improvement

Substances

  • Anti-Bacterial Agents