[Pulmonary embolism and disseminated intravascular coagulation after being bitten by a Bothrops lanceolatus snake. Apropos of a case]

Arch Mal Coeur Vaiss. 1989 Nov;82(11):1903-5.
[Article in French]

Abstract

The authors report the case of a Bothrops lanceolatus snake bite complicated by severe pulmonary embolism a few hours after admission. This thromboembolic complication developed despite heparin therapy and was followed by disseminated intravascular coagulation (DIC). Vascular thrombosis and pulmonary embolism are rare after Bothrops lanceolatus snake bite as patients are usually hypocoagulable due to DIC. In this case, the thromboembolism was probably caused by the procoagulant effect of the thrombin-like enzymes of the snake venom which may have been injected directly into the vein of a young woman taking a contraceptive pill. A specific antivenin which has recently become available fort treatment may decrease the complications of Bothrops lanceolatus snake bite.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antivenins / therapeutic use
  • Blood Coagulation / drug effects
  • Contraceptives, Oral, Hormonal
  • Disseminated Intravascular Coagulation / drug therapy
  • Disseminated Intravascular Coagulation / etiology*
  • Drug Synergism
  • Female
  • Heparin / therapeutic use
  • Humans
  • Pulmonary Embolism / drug therapy
  • Pulmonary Embolism / etiology*
  • Snake Bites / complications*
  • Snake Venoms / pharmacokinetics*

Substances

  • Antivenins
  • Contraceptives, Oral, Hormonal
  • Snake Venoms
  • Heparin